-Tali is a confirmed squadmate
"Garrus, Liara, Kaidan, Ashley and (newly confirmed) Tali are all full
time members of your team if they survived the previous games."
-Wrex?
"I asked point blank about Wrex and got as close to a 'no' as I think Bioware will come at this early stage: exceutive producer Casey Hudson simply re-emphasised that such characters canplay a role and fight alongside you without necessarily being permanent squad members."
-No new Romance in ME3
-Biotics are more potent in combat
"Biotics can use their Pull ability to rip a shield out of someone's hands"
-Multi Layered combat areas
"The games combat spaces have graduated from the often-familiar open areas dotted with low walls. They're now multi layed encouraging you to seek high ground for a better vantage point...[the rest is about Cerberus rocket boot dudes using this to their advantage]
-class Specific Melee attacks
Engineer: Omni-tool fire lash attack
Adept: Melee (biotic) attack that knocks everyone near them away and stuns
-Powers Evolve more than once
"In ME3 this is just the start. A Vanguard player can customise their devastating Charge move first to slam people harder, then do more damage, then to reduce the cooldown.
-Powers combine
Example given with Soldier: "Soldier still has an arcing attack called Concussive Shot, but it now behaves differently depending on the ammo ugrade he/she is using. Cryo ammo lets you use that same trajectory to deliver a blast of ice that canfreeze every enemy in the area."
-Story is more like ME1 than ME2
-Places being visited (at least what the Magazine reports):
[...]mission takes you to the Salarian homeworld, the Quarian homeworld, the Asari homeworld, and the human homeworld - Earth. You'll even go to Mars [...]
-Every major character you have met will play a role in the last game
-Why is Cerberus after Shepard? They are working with the Reapers
"If your wondering why we were fighting Cerberus, having worked closely with this shadowy organisation in Mass Effect 2, the answer just raises further questions. They are wokring with the Reapers"
-Reaperized enemies include Asari, Krogan, Rachni
"In Mass Effect 3 we'll fight the Reapers other experiments, with other species.
One is a hideously bloated pregnant Asari, her gums stripped away and a robot skeleton showing through her rotting flesh"
"The Reapers take on the Rachni, who were already viscious insect monsters,are covered with bulging savs of lesser creatures. Rather than hitting their weak spot for massive damage, you want to avoid it like the plague: bursting any of these sacs before the creature is dead wit will unleash a swarm of horrible mini-rachni that crawl all over your body"
"The Reaperised Krogan wears heavy armor plates that can shear off with enough focused fire. Once you do the creature changes its behaviour to be more defensive clutching its lurid blue intestines to its stomach as its lumbers towards you"
"One Reaper creature draws life force from anything that dies near it.
The time-honoured strategy of taking out the easy enemies first ends up
being counter-productive: you make the creature stronger than it would
have been with its allies alive."
Casey Hudson summarizing ME3 (This is an article quote):
"Casey sums up Mass Effect 3 as being about victory through sacrifice, the scale of that sacrifice has been increasing with each new chapter" [Rest is authors speculation about saving(or not saving) Wrex and Rachni consequences